I came across this paper by Jacques Prudhomme and Karine Le Roche (of P. falciparum transcriptome fame) in which they give evidence that a compound derived from the marine actinomycete Salinospora tropica called salinosporamide A inhibits the parasite proteosome and effectively kills P. yoelii yoelii in an in vivo mouse model.

PLoS ONE. 2008 Jun 4;3(6):e2335

-tmt